i-pill has no long-term or serious side effects, and is safe to use for almost every woman.

Nausea, vomiting, lower abdominal pain, a feeling of breast tenderness and headache are some common side effects after taking i-pill. All this should stop within a day or two. There are chances of unexpected vaginal bleeding, but this is not dangerous and should clear up by the time of the next period. i-pill might also cause the next period to come early or later than normal. But if the periods are delayed by more than a week, it is recommended to go in for a pregnancy test. i-pill will have no lasting effect that may complicate future (and wanted) pregnancies.

i-pill is not recommended if you are allergic to levonorgestrel - the medicine used in i-pill.